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A7706512

Trichlorphon solution , analyticalstandard,1.00mg/mlinmethanol , 52-68-6

Synonym(s):
(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester;Metrifonate;Trichlorfon

CAS NO.:52-68-6

Empirical Formula: C4H8Cl3O4P

Molecular Weight: 257.44

MDL number: MFCD00055272

EINECS: 200-149-3

Update time: 2022-07-08

PRODUCT Properties

Melting point: 77-81 °C
Boiling point: 100°C
Density  1.73
vapor pressure  2.1×10-4Pa (20 °C)
refractive index  1.3439
storage temp.  2-8°C
solubility  Freely soluble in water, very soluble in methylene chloride, freely soluble in acetone and in ethanol (96 per cent).
pka 6 (est.)
form  solid
color  Crystals
Water Solubility  Slightly soluble. 1-5 g/100 mL at 21 ºC
Merck  13,9696
BRN  1709434
Stability: Light Sensitive

Description and Uses

Trichlorfon is a colorless crystalline powder. It is soluble in water (120 g/L) and most organic solvents, except aliphatic hydrocarbons. Log Kow = 0.43. Trichlorfon is rapidly converted to dichlorvos by alkalis (2) and then hydrolyzed; DT50 (22 ?C) values at pH 4, 7, and 9 are 510 d, 46 h, and <30 min, respectively.

Trichlorfon is an irreversible organophosophate acetylcholinesterase inhibitor and the prodrug of Dichlorvos (D435950). Trichlorfon have also shown potential actions to be utilized as an effective org anophosphorus pesticide.

Safety

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H302+H312-H317-H334-H410
Precautionary statements  P273-P280-P301+P312+P330-P302+P352+P312
Hazard Codes  Xn,N
Risk Statements  22-43-50/53
Safety Statements  24-37-60-61-2
RIDADR  UN 3077 9/PG 3
WGK Germany  3
RTECS  TA0700000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29319090
Toxicity LD50 in male, female rats (mg/kg): 630, 560 orally (Gaines)

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