1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose , 98% , 13035-61-5

Synonym(s):
1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose

CAS NO.：13035-61-5

Empirical Formula: C13H18O9

Molecular Weight: 318.28

MDL number: MFCD00005358

EINECS: 235-898-5

PRODUCT Properties

• Melting point: 81-83 °C(lit.)
• alpha: -15.4 º (c=7, MeOH)
• Boiling point: 417.45°C (rough estimate)
• Density: 1.4171 (rough estimate)
• refractive index: -14.5 ° (C=5, MeOH)
• storage temp.: Inert atmosphere,Room Temperature
• solubility: Chloroform (Sparingly), Methanol (Slightly)
• form: Crystalline Powder
• color: White to almost white
• optical activity: [α]26/D 11.4°, c = 10 in chloroform
• BRN: 94078
• InChI: InChI=1/C13H18O9/c1-6(14)18-5-10-11(19-7(2)15)12(20-8(3)16)13(22-10)21-9(4)17/h10-13H,5H2,1-4H3/t10-,11-,12-,13-/s3
• InChIKey: TTXVPMATRDJQIA-BKUVIOGVSA-N
• SMILES: [C@@H]1(OC(=O)C)[C@@H](COC(=O)C)O[C@@H](OC(=O)C)[C@@H]1OC(=O)C |&1:0,5,12,17,r|

Description and Uses

beta-D-Ribofuranose 1,2,3,5-tetraacetate is an acetylated derivative of ribose extensively used in carbohydrate research and synthetic chemistry. This compound features acetyl groups protecting the hydroxyl functionalities at positions 1, 2, 3, and 5 of the ribofuranose ring, which enhances its stability and solubility in organic solvents. β-D-Ribofuranose 1,2,3,5-tetraacetate is a crucial intermediate in synthesising nucleosides, nucleotides, and other complex carbohydrates. In research, it is utilized to study glycosylation mechanisms, focusing on the formation and stereochemistry of glycosidic bonds.

beta-D-Ribofuranose 1,2,3,5-tetraacetate is used in the synthesis of 3-(β-D-ribofuranosyl)-2,3-dihydro-6H-1,3-oxazine-2,6-dione, a new pyrimidine nucleoside analog related to uridine.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P280-P261
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• HS Code: 29400090