Home Categories Biochemical Engineering 5-Thio-D-glucose
A7705112

5-Thio-D-glucose , ≥98.0%(HPLC) , 20408-97-3

CAS NO.:20408-97-3

Empirical Formula: C6H12O5S

Molecular Weight: 196.22

MDL number: MFCD00148892

EINECS: 243-798-8

Pack Size Price Stock Quantity
25MG RMB447.20 In Stock
100MG RMB1656.80 In Stock
250mg RMB3519.20 In Stock
1G RMB9999.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 135-138 °C(lit.)
Boiling point: 303.11°C (rough estimate)
Density  1.271 (estimate)
refractive index  1.5060 (estimate)
storage temp.  2-8°C
solubility  Soluble in Water (up to 15 mg/ml)
pka 9.11±0.10(Predicted)
form  Powder
color  White
optical activity [α]/D 220.0±5.0°, c = 1 in 0.1 M HCl
Water Solubility  Miscible with water.
Merck  13,9408
BRN  1865193
Stability: Stable for 2 years as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
CAS DataBase Reference 20408-97-3
EPA Substance Registry System D-Glucose, 5-thio- (20408-97-3)

Description and Uses

5-Thio-D-glucose (20408-97-3) is a potent competitive inhibitor of the cellular transport of glucose and glucose-mediated insulin release.1 May be used to induce a state of glucose deprivation in laboratory animals.2 Stimulates feeding in rat models.3? Induces Alzheimer-like changes in frontal cortex and hippocampus in rats.4? Elevates renal TGF-b1 at a dose that does not prevent streptozotocin diabetes in rats.5

5-Thio-D-glucose (cas# 20408-97-3) is a compound useful in organic synthesis.

Safety

Safety Statements  22-24/25
WGK Germany  3
RTECS  LZ7500000
3-10-23
Toxicity mouse,LD50,intraperitoneal,5500mg/kg (5500mg/kg),International Journal of Radiation Oncology, Biology, Physics. Vol. 8, Pg. 589, 1982.

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