Home Categories Chemical Reagents 1-Thioglycerol
A7716112

1-Thioglycerol , 97%, for cell culture , 96-27-5

Synonym(s):
α-Monothioglycerol;α-Thioglycerol;1-Thioglycerol;3-Mercapto-1,2-propanediol

CAS NO.:96-27-5

Empirical Formula: C3H8O2S

Molecular Weight: 108.16

MDL number: MFCD00004879

EINECS: 202-495-0

Pack Size Price Stock Quantity
5g RMB48.80 In Stock
25G RMB174.40 In Stock
100G RMB520.00 In Stock
500g RMB2014.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: <25 °C
Boiling point: 118 °C5 mm Hg(lit.)
Density  1.25 g/mL at 25 °C(lit.)
vapor pressure  <1 hPa (20 °C)
refractive index  n20/D 1.527(lit.)
Flash point: >230 °F
storage temp.  2-8°C
solubility  absolute ethanol: 1 mL/mL
form  liquid
pka pK1:9.43 (25°C,μ=0.5)
color  Clear colorless to yellow
Odor Stench odour
PH 3.5-7.0
Water Solubility  slightly soluble
Sensitive  Air Sensitive & Hygroscopic
Merck  14,9335
BRN  1732046
Stability: Air Sensitive, Hygroscopic
InChIKey PJUIMOJAAPLTRJ-UHFFFAOYSA-N
LogP -0.84 at 20℃

Description and Uses

1-Thioglycerol is a reagent used in fluorescence, spectroscopy, and microbiology techniques. Varying the concentration of 1-thioglycerol in the preparation of CdSe/CdS core-shell ultrasmall quantum dots (CS-USQDs) allows a precise way to control the size of the shell, with shell size increasing with increased concentration. It is used as a capping agent in the synthesis of nanocrystals analyzed via Raman and UV/Vis spectroscopy. Biologically, 1-thioglycerol stimulates porphyrin synthesis and increases glutamyl-tRNA reductase activity in E. coli grown in an aerobic environment. It was previously a component in hair permanents used to produce waves or curls.

It generally used as a size-regulating capping agent for nanocrystals. 1-Thioglycerol is also used in bacteriology experiments to induce the synthesis of porphyrin compounds in aerobically growing Escherichia coli. Also used to study the pH-sensitive photoluminescence of aqueous thiol-capped CdTe nanocrystals. 1-Thioglycerol is used to develop and test thiol functionalized copolymers. 1-Thioglycerol is used as a post-modification agent in the generation of non-standard peptide foldamers.Potential substitute for 2-mercaptoethanol, probe for the study of lymphocyte activation.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H302-H311-H315-H317
Precautionary statements  P280-P301+P312+P330-P302+P352+P312
Hazard Codes  Xn,Xi
Risk Statements  21/22-36/37/38
Safety Statements  26-36-23
RIDADR  UN 2810 6.1/PG 3
WGK Germany  3
RTECS  TY8140000
3-9-10-13-23
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29309070

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