ParomomycinSulfate , 10mMinWater , 1263-89-4
Synonym(s):
Aminosidine sulfate;Neomycin E;Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem;Paromomycin sulfate salt
CAS NO.：1263-89-4
Empirical Formula: C23H47N5O18S
Molecular Weight: 713.71
MDL number: MFCD00079278
EINECS: 215-031-7
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 145 °C (decomp) |
| alpha | D25 +50.5° (c = 1.5 in water pH 6) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: 50 mg/mL store stock solution at 2-8°C. Stable at 37°C for 5 days. |
| form | powder |
| color | White to Off-White |
| Water Solubility | Soluble in water |
| Merck | 14,7041 |
| BRN | 5715182 |
| Stability: | Hygroscopic |
| InChIKey | LJRDOKAZOAKLDU-UDXJMMFXSA-N |
| CAS DataBase Reference | 1263-89-4 |
| EPA Substance Registry System | Paromomycin sulfate (1263-89-4) |
Description and Uses
Paromomycin was found in the culture broth of Streptomyces rimosus forma paromomycinus by Parke Davis & Co. in 1959. In the same year it was found in the culture broth of S. Crestomyceticus by Farmitalia and named amminosidin. Paromomycin is related structurally to neomycin, but it has a hydroxyl group at the 6 position, whereas neomycin has an amino group. Its antibacterial activity is weaker than that of neomycin, but its toxicity is much less. Paromomycin is used by intramuscular injection for therapy of respiratory, urinary, and surgical infections and by oral administration to treat dysentery and salmonellosis.
PAROMOMYCIN SULFATE is an aminogycoside antibiotic designed to fight intestinal infections such as cryptosporidiosis, amoebiasis, and leishmaniasis. Its antiprotozoal activity makes it an effecive histomonostatic feed addit ive in turkey poults experimentally infected with Histomonas meleagridis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 23/24/25-36/38-39/23/24/25-61-36/37/38 |
| Safety Statements | 26-36/37-45-38-36 |
| WGK Germany | 2 |
| RTECS | WK2320000 |
| HS Code | 2941901010 |
| Toxicity | LD50 in mice (mg/kg): ~15,000 orally; 700 s.c.; 110 i.v. (Di Marco, Bertazzoli) |
