PulchinenosideC , 2mMinDMSO , 129741-57-7
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB232.80 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 208-215℃ |
| Density | 1.48 |
| solubility | DMSO : 125 mg/mL (102.34 mM; Need ultrasonic) |
| form | Powder |
| pka | 12.50±0.70(Predicted) |
| color | White to light yellow |
Description and Uses
Pulchinenoside B4 is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities. It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM. Pulchinenoside B4 (50 and 100 mg/kg twice per day) prevents increases in plasma blood urea nitrogen (BUN) and creatinine levels, markers of kidney injury, in a mouse model of cisplatin-induced nephrotoxicity. It prevents xylene-induced ear edema in mice in a dose-dependent manner. Pulchinenoside B4 (50 mg/kg) inhibits LPS-induced increases in serum TNF-α, IL-6, and IL-1β levels a mouse model of LPS-induced systemic inflammation.
Pulchinenoside C is a triterpenoid saponin extract which acts as a minor molluscicidal agent in addition to tumor necrosis factor-α secretion inhibition. Anti-inflammatory.
