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A7668712

trichloroacetic acid , AR,99.0% , 76-03-9

Synonym(s):
TCA;Trichloroacetic acid;Trichloroacetic Acid - CAS 76-03-9 - Calbiochem

CAS NO.:76-03-9

Empirical Formula: C2HCl3O2

Molecular Weight: 163.39

MDL number: MFCD00004177

EINECS: 200-927-2

Update time: 2022-07-08

PRODUCT Properties

Melting point: 54-58 °C (lit.)
Boiling point: 196 °C (lit.)
Density  1.62 g/mL at 25 °C (lit.)
vapor density  <1 (vs air)
vapor pressure  1 mm Hg ( 51 °C)
refractive index  n20/D 1.62(lit.)
Flash point: 196°C
storage temp.  Store at +15°C to +25°C.
solubility  H2O: 0.5 M at 20 °C, clear, colorless
form  Solid
pka 0.7(at 25℃)
color  White
PH <1.0 (25℃, 0.5M in H2O)
Odor sharp, pungent odor
Water Solubility  120 g/100 mL (20 ºC)
Sensitive  Hygroscopic
λmax 210nm(EtOH)(lit.)
Merck  14,9627
BRN  970119
Exposure limits ACGIH: TWA 0.5 ppm
NIOSH: TWA 1 ppm(7 mg/m3)
Dielectric constant 4.9(20℃)
Stability: Stable, but moisture sensitive. Incompatible with water, strong bases. Note that the Merck Index states that this material is hydrolytically unstable in aqueous solution below 30% by weight. Decomposition products include carbon monoxide and carbon dioxide. The generation of these gases in a sealed container may lead to a pressure rise sufficien
LogP 1.330

Description and Uses

Trichloroacetic acid, also known as TCA or 76-03-9, is a colorless or white orthorhombic crystal with strong deliquescence and a slight, special irritant smell. It is highly corrosive. TCA's aqueous solution is strongly acidic, with a pH of 1.2 for a 0.1 mol solution. Concentrations of TCA at or below 30% cannot be stored for long periods due to decomposition into chloroform, hydrogen chloride, carbon dioxide, and carbon monoxide. Dilute alkali leads to hydrolysis into chloroform and carbon dioxide. Concentrated alkali results in the formation of formic acid. TCA is a highly toxic substance with an oral LD50 of 3320mg/kg.

As a reagent for albumin detection; in making herbicides. It is found as a by-product after chlorination of water containing humic materials.

Safety

Symbol(GHS) 
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H314-H335-H410
Precautionary statements  P260-P271-P273-P280-P303+P361+P353-P305+P351+P338
Hazard Codes  Xn,N,C,F,Xi
Risk Statements  36/37/38-40-51/53-50/53-35-38-11-34-67-52/53
Safety Statements  26-36/37-61-60-45-36/37/39-24/25-16
OEB B
OEL TWA: 1 ppm (7 mg/m3)
RIDADR  UN 1839 8/PG 2
WGK Germany  2
RTECS  AJ7875000
10-21
Autoignition Temperature 711 °C
Hazard Note  Corrosive/Hygroscopic
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29154000
Toxicity LD50 orally in rats: 5000 mg/kg (Bailey, White)

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