Tetracaine hydrochloride , 99% , 136-47-0

Synonym(s):
4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester;Amethocaine hydrochloride

CAS NO.：136-47-0

Empirical Formula: C15H25ClN2O2

Molecular Weight: 300.82

MDL number: MFCD00038912

EINECS: 205-248-5

PRODUCT Properties

• Melting point: 149°C
• Density: 1.1279 (rough estimate)
• refractive index: 1.5200 (estimate)
• storage temp.: 2-8°C
• solubility: alcohol: solublesoluble 40 parts of solvent
• form: Solid
• pka: 8.39(at 25℃)
• color: White to Almost white
• Water Solubility: Soluble in water at 50mg/ml
• Merck: 14,9188
• InChI: InChI=1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
• InChIKey: PPWHTZKZQNXVAE-UHFFFAOYSA-N
• SMILES: C1(C=CC(NCCCC)=CC=1)C(=O)OCCN(C)C.Cl
• LogP: 3.649 (est)
• CAS DataBase Reference: 136-47-0(CAS DataBase Reference)
• EPA Substance Registry System: Tetracaine hydrochloride (136-47-0)

Description and Uses

Tetracaine hydrochloride is a local anesthetic used topically in opthalmology.It is a highly effective local anesthetic that reversibly blocks nerve function. It is clinically used for infiltration anesthesia, nerve block anesthesia, epidural anesthesia, etc. Compared with procaine, its local anesthesia effect is remarkable. Tetracaine hydrochloride has been widely used in clinical practice.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301-H319-H336
• Precautionary statements: P261-P264-P270-P271-P301+P310-P305+P351+P338
• Hazard Codes: T
• Risk Statements: 25-36-43-42/43
• Safety Statements: 26-36/37-45-36/37/39-22-53
• RIDADR: 2811
• WGK Germany: 3
• RTECS: DG4900000
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29224999
• Toxicity: LD50 i.p. in mice: 70 mg/kg (Dawes); also reported as LD50 in female mice (mg/kg): 13 i.v.; 35 s.c. (Bopp)