PRODUCT Properties
| Melting point: | 110-115 °C (lit.) |
| alpha | [α]D20 -1～+1° (c=5, C2H5OH) |
| Boiling point: | 164.01°C (rough estimate) |
| Density | 1.0951 (rough estimate) |
| refractive index | 1.4240 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 4.13(at 25℃) |
| color | White to Off-White |
| PH | 3.62(1 mM solution);3.08(10 mM solution);2.57(100 mM solution) |
| Water Solubility | Soluble in water. |
| BRN | 1722946 |
| Stability: | Stable. Combustible. Incompatible with bases, oxidizing agents, reducing agents. |
| CAS DataBase Reference | 498-21-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Butanedioic acid, methyl-(498-21-5) |
| EPA Substance Registry System | Butanedioic acid, 2-methyl- (498-21-5) |
Description and Uses
Methylsuccinic acid is a normal metabolite found in human fluids and is an intermediate metabolite in the breakdown of fatty acids. Increased urinary levels of methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy.
Methylsuccinic acid is used as a flux material and an important dyestuff intermediate. It is also used as an intermediate in medicine and pharmaceuticals.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29171900 |
