Methylboronic acid , 97% , 13061-96-6

Synonym(s):
Methaneboronic acid

Update time: 2022-07-08

Melting point:	91-94 °C (lit.)
Boiling point:	141.7±23.0 °C(Predicted)
Density	0.965±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO, Water
pka	9.97±0.43(Predicted)
form	Crystalline Powder
color	White to off-white
Water Solubility	Soluble in water.
Sensitive	Hygroscopic
BRN	1731087
InChI	InChI=1S/CH5BO2/c1-2(3)4/h3-4H,1H3
InChIKey	KTMKRRPZPWUYKK-UHFFFAOYSA-N
SMILES	CB(O)O
CAS DataBase Reference	13061-96-6(CAS DataBase Reference)

Methylboronic acid can be used as a reagent:

In the palladium-catalyzed Stille and Suzuki-Miyaura cross-couplings.
In the microwave-heated heterogeneous palladium (Pd)-catalytized reactions.
In ruthenium (Ru)-catalyzed silylation reactions
To prepare bis(aminotropone) titanium (Ti) catalysts for ethylene polymerizations.
In the enantioselective asymmetric bromoaminocyclization and bromoaminocyclization using amino-thiocarbamate catalysts.
To prepare common building blocks for pharmaceuticals and agrochemicals.
To prepare chrysin analogs by Suzuki-Miyaura coupling reactions.
To prepare casein kinase I inhibitors.
In the divergent C-H functionalizations directed by sulfonamide pharmacophores in drug discovery.
In the synthesis of unsymmetrical monosulfides from disulfides via copper-catalyzed coupling with boronic acids.
In a palladium-catalyzed coupling with enol tosylates.
For derivatizing many carbohydrates and biologically active compounds for GLC analysis.