A7635812
Tobramycin , Potency≥900μG/mg,98% , 32986-56-4
Synonym(s):
Nebramycin Factor 6;O-[3-Amino-3-deoxy-α-D -glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D -ribohexopyranosyl-(1→4)]-2-deoxy-D- streptamine;Tobramycin, Free Base - CAS 32986-56-4 - Calbiochem
CAS NO.:32986-56-4
Empirical Formula: C18H37N5O9
Molecular Weight: 467.52
MDL number: MFCD00077885
EINECS: 251-322-5
Pack Size | Price | Stock | Quantity |
1G | RMB74.40 | In Stock |
|
5G | RMB192.80 | In Stock |
|
25G | RMB564.80 | In Stock |
|
100g | RMB1952.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 178 °C |
alpha | D20 +129° (c = 1 in water) |
Boiling point: | 570.01°C (rough estimate) |
Density | 1.3458 (rough estimate) |
refractive index | 143 ° (C=4, H2O) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | H2O: 50 mg/mL, clear, faintly yellow |
pka | pKa 6.7 (Uncertain);8.3 (Uncertain);9.9 (Uncertain) |
form | White to off-white solid |
color | white to off-white |
Water Solubility | Soluble in water |
Merck | 14,9490 |
BRN | 1357507 |
Stability: | Hygroscopic |
Description and Uses
Tobramycin is one component (factor 6) of a mixture produced by fermentation of Streptomyces tenebrari us. Lacking the C-3′ hydroxyl group, it is not a substrate for APH(3′)-1 and APH(3′)-II and so has an intrinsically broader spectrum than kanamycin. It is a substrate, however, for adenylation at C-2′ by ANT (2′) and acetylation at C-3 by AAC(3)-I and AAC(3)-II and at C-2′ by AAC(2′).
Antihypertensive
Safety
Symbol(GHS) | GHS08 |
Signal word | Warning |
Hazard statements | H361f |
Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-37/39 |
WGK Germany | 2 |
RTECS | WK2100000 |
F | 3-10 |
HS Code | 29419090 |
Hazardous Substances Data | 32986-56-4(Hazardous Substances Data) |
Toxicity | LD50 in mice, rats (mg/kg): 441, 969 s.c. (Welles) |