PRODUCT Properties
| Melting point: | 178-182° (dec) |
| alpha | D18 +130° (c = 0.5 in water); D21 +114° (c = 0.98 in water) |
| Boiling point: | 580.49°C (rough estimate) |
| Density | 1.3771 (rough estimate) |
| refractive index | 1.7600 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Aqueous Acid (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 13.07±0.70(Predicted) |
| color | Crystals |
| Stability: | Hygroscopic |
Description and Uses
Bekanamycin, kanamycin B, was found in the culture broth of Streptomyces kanamyceticus by Umezawa et al. in 1957. It shows the same antibacterial spectrum as kanamycin but with stronger activity. The total synthesis of bekanamycin was completed by Umezawa et al. in 1968 and the knowledge gained from its synthesis was successfully applied to the synthesis of dibekacin.
Kanamycin B (cas# 4696-76-8) is a compound useful in organic synthesis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315; H319; H335 |
| Precautionary statements | P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501 |
| Toxicity | LD50 i.v. in mice: 136 mg/kg (Wakazawa) |
