A7628358
Paeoniflorin , 10mMinDMSO , 23180-57-6
Synonym(s):
NSC 178886;Peoniflorin
CAS NO.：23180-57-6
Empirical Formula: C23H28O11
Molecular Weight: 480.47
MDL number: MFCD00869331
EINECS: 245-476-2
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | approximate 124℃ (dec.) |
| Boiling point: | 498.51°C (rough estimate) |
| Density | 1.3044 (rough estimate) |
| refractive index | 1.5376 (estimate) |
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly, Sonicated), Pyridine (Slightly) |
| form | powder |
| pka | 11.52±0.70(Predicted) |
| color | white |
| InChIKey | YKRGDOXKVOZESV-WRJNSLSBSA-N |
Description and Uses
Paeoniflorin is an active compound of the Paeonia root. Paeoniflorin inhibits Aβ25-35-induced mitochondrial dysfunction, which includes decreased mitochondrial membrane potential, increased Bax/Bcl-2 ratio, cytochrome c release and activity of caspase-3 and caspase-9. Paeoniflorin could attenuate or restore the viability loss, apoptotic increase, and ROS production induced by Aβ25-35 in SH-SY5Y cells.
Safety
| Symbol(GHS) |   GHS07,GHS02 |
| Signal word | Warning |
| Hazard statements | H315-H319-H226 |
| Precautionary statements | P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | RT1200000 |
| HS Code | 29389090 |
| Toxicity | LD50 ipr-mus: 9530 mg/kg YKKZAJ 89,879,69 |
