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A7614658

Lumefantrine , 10mMinDMSO , 82186-77-4

Synonym(s):
(9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol;Benflumetol;CPG-56695;Lumefantrine

CAS NO.:82186-77-4

Empirical Formula: C30H32Cl3NO

Molecular Weight: 528.94

MDL number: MFCD05662268

EINECS: 617-303-4

Pack Size Price Stock Quantity
1ml RMB239.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 129-131°C
Boiling point: 642.5±55.0 °C(Predicted)
Density  1.252
storage temp.  15-25°C
solubility  DMSO: ≥20mg/mL
pka 13.44±0.20(Predicted)
form  powder
color  yellow
Merck  14,5597
CAS DataBase Reference 82186-77-4(CAS DataBase Reference)

Description and Uses

Lumefantrine is a derivative of halofantrine that has been reported to exhibit antimalarial activity when combined with artemether in the treatment of multidrug-resistant Plasmodium falciparium . No evidence of cardiotoxicity has been reported with this combination, which may offer promise for successful treatment of resistant organisms.

Lumefantrine has been used:
to study its effect on ex-vivo?Plasmodium falciparum?sensitivity using the tritiated hypoxanthine-based assay
as a standard in the quantification of combined tablet formulation using HPTLC
as a drug molecule in in vitro growth inhibition assay for in vitro B. caballi?growth inhibition studies

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
HS Code  29221950
Hazardous Substances Data 82186-77-4(Hazardous Substances Data)

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