Methyl 4-hydroxybenzoate , Used for insect cell culture, ≥99.0% , 99-76-3

Synonym(s):
Methyl paraben;Methyl 4-hydroxybenzoate;NIPAGIN;p-Hydroxybenzoic acid methyl ester;Methylis parahydroxybenzoas

CAS NO.：99-76-3

Empirical Formula: C8H8O3

Molecular Weight: 152.15

MDL number: MFCD00002352

EINECS: 202-785-7

PRODUCT Properties

• Melting point: 125-128 °C (lit.)
• Boiling point: 298.6 °C
• Density: 1,46g/cm
• vapor pressure: 0.000005 hPa (20 °C)
• refractive index: 1.4447 (estimate)
• FEMA: 2710 | METHYL P-HYDROXYBENZOATE
• Flash point: 280°C
• storage temp.: room temp
• solubility: ethanol: soluble0.1M, clear, colorless
• pka: pKa 8.15(H2O,t =20.0) (Uncertain)
• form: Crystalline Powder
• color: White to almost white
• PH: 5.8 (H2O, 20°C) (saturated solution)
• Odor: odorless or faint char. odor, sl. burning taste
• Water Solubility: Slightly soluble in water.
• FreezingPoint: 131℃
• Merck: 14,6107
• BRN: 509801
• Stability: Stable. Incompatible with strong oxidizing agents, strong bases.
• InChIKey: LXCFILQKKLGQFO-UHFFFAOYSA-N
• LogP: 1.98 at 20℃
• CAS DataBase Reference: 99-76-3(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-hydroxy-, methyl ester(99-76-3)
• EPA Substance Registry System: Methylparaben (99-76-3)

Description and Uses

Methyl 4-hydroxybenzoate is used as an anti-fungal agent. It is also used as a preservative in foods, beverages and cosmetics. It acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.

Safety

• Symbol(GHS): GHS09
• Signal word: Warning
• Hazard statements: H411
• Precautionary statements: P273-P391-P501
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22-36
• Safety Statements: 26-36-24/25-39
• RIDADR: UN 2769
• WGK Germany: 1
• RTECS: DH2450000
• Autoignition Temperature: >600 °C
• TSCA: Yes
• HS Code: 29182930
• Hazardous Substances Data: 99-76-3(Hazardous Substances Data)
• Toxicity: LD50 orally in Rabbit: 2100 mg/kg