A7607458
Gap27 , 10mMinDMSO , 198284-64-9
Synonym(s):
Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile
CAS NO.:198284-64-9
Empirical Formula: C60H101N15O17
Molecular Weight: 1304.53
MDL number: MFCD03456920
Pack Size | Price | Stock | Quantity |
1ml | RMB559.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Density | 1.40±0.1 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | Soluble at 1mg/ml in 1% acetic acid |
pka | 3.41±0.10(Predicted) |
form | Solid |
color | White to off-white |
Water Solubility | Soluble to 1 mg/ml in water |
Sequence | H-Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile-OH |
Description and Uses
Gap27 is a connexin (Cx) mimetic peptide that inhibits connexin-mediated communication (CMC). In vitro, Gap27 has been shown to improve cell migration during scrape-wound repair in hyperglycemia/hyperinsulinemia conditions. It also reduces acetylcholine-induced hyperpolarization in smooth muscle cells.
Safety
Safety Statements | 22-24/25 |
WGK Germany | 3 |