4-Hexylresorcinol , 10mMinDMSO , 136-77-6

Synonym(s):
1,3-Dihydroxy-4-hexylbenzene, 1,3-Dihydroxy-4-hexylbenzene;4-Hexyl-1,3-dihydroxybenzene;4-Hexylresorcinol;Antascarin;Ascarinol

CAS NO.：136-77-6

Empirical Formula: C12H18O2

Molecular Weight: 194.27

MDL number: MFCD00002284

EINECS: 205-257-4

PRODUCT Properties

• Melting point: 65-67 °C (lit.)
• Boiling point: 333-335 °C (lit.)
• Density: 1.0010 (rough estimate)
• vapor pressure: 0.001Pa at 25℃
• refractive index: 1.5050 (estimate)
• Flash point: >100°C
• storage temp.: 2-8°C
• solubility: chloroform: 50 mg/mL, clear
• pka: pKa 9.1 (Uncertain)
• form: Powder and/or Chunks
• color: White to pale orange or pale pink
• PH: 7.7 (0.5g/l, H2O, 20℃)
• Water Solubility: 0.05 g/100 mL (18 ºC)
• Merck: 14,4712
• BRN: 2048312
• Stability: Stable. Incompatible with acid chlorides, acid anhydrides, oxidizing agents.
• InChIKey: WFJIVOKAWHGMBH-UHFFFAOYSA-N
• LogP: 3.34 at 20℃
• Surface tension: 36.59mN/m at 1g/L and 20℃

Description and Uses

4-Hexylresorcinol is an inhibitor of transglutaminase-2 in KB cells. Studies indicate that 4-Hexylresorcinol reduces DNA oxidative damage in human lymphocytes. is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections. is a substituted phenol with bactericidal, antihelminthic and potential antineoplastic activities. The combination of 4-Hexylresorcinol and Cisplatin has been shown to inhibit tumor growth, cell growth, and KB cell viability.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H319-H411
• Precautionary statements: P264-P270-P273-P280-P301+P312-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22-36/37/38-20/21/22
• Safety Statements: 26-36-24/25
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• RTECS: VH1575000
• TSCA: Yes
• HS Code: 29072900
• Toxicity: LD50 orally in Rabbit: 550 mg/kg