GinsenosideRg3 , 10mMinDMSO , 38243-03-7
Pack Size | Price | Stock | Quantity |
1ml | RMB559.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 315-318 ºC |
Boiling point: | 885.0±65.0 °C(Predicted) |
Density | 1.30 |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | Chloroform (Very Slightly, Heated Sonicated), Pyridine (Slightly, Heated, Sonicated) |
form | Solid |
pka | 12.85±0.70(Predicted) |
color | White to Off-White |
Stability: | Hygroscopic |
InChIKey | VMFHKVMQSYOBAV-KQVQOVSDNA-N |
Description and Uses
Ginsenoside Rg3 is mainly derived from the dried roots of Araliaceae Panax ginseng C.A.?Mey. and Panax quinquefolius L.?Ginseng has a long history of medicinal uses, well known as “king of herbs.” Ginseng is listed as the top grade in “Shen Nong’s herbal class,” with “the main security set up the five internal organs, spirit, soul, stop fright, in addition to evil, eyesight, fun puzzle” account. The traditional Chinese medicine regards ginseng as the top grade of reinforcing Qi, with Dabu strength, spleen and lungs, Sheng Jin, Anshen Yizhi, etc.
20(R)-Ginsenoside Rg3 causes an inhibition of phosphatidylinositol 3-kinase/Akt activation that, in turn, results in modulations in Bcl-2 family proteins in such a way that the apoptosis of U87 cells are regulated. Elicits a significant inhibition of in vitro cell adhesion and invasion of U87 cells. in vitro stereoselective inhibition of ginsenosides toward UDP-glucuronosyltransferase isoforms and in vivo inhibition of tumor angiogenesis of lung cancer.