FAAH-IN-2 , 10mMinDMSO , 184475-71-6

CAS NO.：184475-71-6

Empirical Formula: C15H11ClFN3O2

Molecular Weight: 319.72

MDL number: MFCD09908046

EINECS: 1806241-263-5

PRODUCT Properties

• Melting point: >260°C (dec.)
• Boiling point: 478.8±45.0 °C(Predicted)
• Density: 1.489±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• solubility: DMSO (Slightly), Methanol (Very Slightly, Heated)
• form: Solid
• pka: 8.18±0.40(Predicted)
• color: Pale Beige to Beige

Description and Uses

O-Desmorpholinopropyl Gefitinib is a metabolite of Gefitinib, a potent inhibitor of tyrosine phosporylation in EGFR. The chemical structure of O-Desmorpholinopropyl Gefitinib consists of a quinazoline-6-ol core with a phenylamino group attached to a chloro-fluoro-phenyl ring, enabling it to interact with multiple biological targets. It is involved in inhibiting enzymes such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS).

A metabolite of Gefitinib.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• HS Code: 2933.59.8000