Home Categories API 2-(2-Methylaminoethyl)pyridine
A7584558

2-(2-Methylaminoethyl)pyridine , 10mMinDMSO , 5638-76-6

CAS NO.:5638-76-6

Empirical Formula: C8H12N2

Molecular Weight: 136.19

MDL number: MFCD00006362

EINECS: 227-086-4

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Boiling point: 113-114 °C30 mm Hg(lit.)
Density  0.984 g/mL at 25 °C(lit.)
vapor pressure  17.7Pa at 25℃
refractive index  n20/D 1.518(lit.)
Flash point: 206 °F
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Chloroform (Slightly), DMSO (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka pKa 3.46 (Uncertain)
form  Oil
color  Light Yellow to Yellow
Water Solubility  1000g/L at 25℃
Merck  13,1181
LogP 0.68
CAS DataBase Reference 5638-76-6(CAS DataBase Reference)
EPA Substance Registry System 2-Pyridineethanamine, N-methyl- (5638-76-6)

Description and Uses

Betahistine is an analogue of histamine with weak agonist properties at histamine H1 receptors and more potent antagonistic effects at histamine H3 receptors.
This drug is broadly used worldwide, except for the USA, since it has not been approved by the US Food and Drug Administration. Betahistine is a structural analog of histamine that acts as a weak partial postsynaptic histamine H1 receptor agonist and presynaptic H3 receptor antagonist, with no effect on postsynaptic H2 receptors (Gbahou et al, 2010). The mechanism of action of the drug appears to depend mainly on its action on H3 receptors mediated by two metabolites, aminoethylpyridine and hydroxyethylpyridine (Bertich et al, 2014).

Anti - Vertigo/Anti-Nauseants/Antiemetics

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,C
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  2
RTECS  UT5552000
Hazard Note  Corrosive
HS Code  2933399990

RELATED PRODUCTS