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A7475112

Shikonin , 98%(HPLC) , 54952-43-1

CAS NO.:54952-43-1

Empirical Formula: C16H16O5

Molecular Weight: 288.3

MDL number: MFCD00016668

Pack Size Price Stock Quantity
10MG RMB244.80 In Stock
50MG RMB682.40 In Stock
250mg RMB3199.20 In Stock
500mg RMB5759.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 144-145 °C
Boiling point: 567.4±50.0 °C(Predicted)
Density  1.373±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  methanol: soluble1mg/mL
pka 7.34±0.20(Predicted)
form  powder or solid
color  red to brown
LogP 4.350 (est)

Description and Uses

Shikonin has been used:

  • to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
  • as an inhibitor of renal aerobic glycosis and a potential
  • as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
  • to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death

Safety

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H400
Precautionary statements  P273-P301+P312+P330
Hazard Codes  Xn,N
Risk Statements  22-50/53
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3

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