Seleno-<SC>L</SC>-cystine , 95% , 29621-88-3
Synonym(s):
(R,R)-3,3′-Diseleno-bis(2-aminopropionic acid);L -Selenocystine
CAS NO.:29621-88-3
Empirical Formula: C6H12N2O4Se2
Molecular Weight: 334.09
MDL number: MFCD00800971
EINECS: 608-382-6
Pack Size | Price | Stock | Quantity |
50MG | RMB183.20 | In Stock |
|
250MG | RMB639.20 | In Stock |
|
1G | RMB1164.00 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 224.5-229.5 °C (lit.) |
Boiling point: | 538.3±60.0 °C(Predicted) |
storage temp. | 2-8°C |
solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) |
form | Powder |
pka | 1.69±0.10(Predicted) |
color | Yellow |
optical activity | [α]20/D 28°, c = 1 in NaOH |
BRN | 1969559 |
Stability: | Hygroscopic |
Description and Uses
L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.
Seleno-L-cystine can be used for the synthesis of:
- Biologically active selenol compounds.
- Non-natural selenylated diamino acids.
Safety
Symbol(GHS) | GHS06,GHS08,GHS09 |
Signal word | Danger |
Hazard statements | H301+H331-H373-H410 |
Precautionary statements | P273-P301+P310+P330-P304+P340+P311-P314 |
Hazard Codes | T,N |
Risk Statements | 23/25-33-50/53 |
Safety Statements | 20/21-28-45-60-61 |
RIDADR | UN 3283 6.1/PG 3 |
WGK Germany | 3 |
RTECS | AY6032000 |
HazardClass | 6.1 |
PackingGroup | III |
HS Code | 29319090 |