Home Categories Chemical Reagents Seleno-<SC>L</SC>-cystine
A7471612

Seleno-<SC>L</SC>-cystine , 95% , 29621-88-3

Synonym(s):
(R,R)-3,3′-Diseleno-bis(2-aminopropionic acid);L-Selenocystine

CAS NO.:29621-88-3

Empirical Formula: C6H12N2O4Se2

Molecular Weight: 334.09

MDL number: MFCD00800971

EINECS: 608-382-6

Pack Size Price Stock Quantity
50MG RMB183.20 In Stock
250MG RMB639.20 In Stock
1G RMB1164.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 224.5-229.5 °C (lit.)
Boiling point: 538.3±60.0 °C(Predicted)
storage temp.  2-8°C
solubility  Aqueous Acid (Slightly), Aqueous Base (Slightly)
form  Powder
pka 1.69±0.10(Predicted)
color  Yellow
optical activity [α]20/D 28°, c = 1 in NaOH
BRN  1969559
Stability: Hygroscopic

Description and Uses

L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.

Seleno-L-cystine can be used for the synthesis of:

  • Biologically active selenol compounds.
  • Non-natural selenylated diamino acids.

Safety

Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H331-H373-H410
Precautionary statements  P273-P301+P310+P330-P304+P340+P311-P314
Hazard Codes  T,N
Risk Statements  23/25-33-50/53
Safety Statements  20/21-28-45-60-61
RIDADR  UN 3283 6.1/PG 3
WGK Germany  3
RTECS  AY6032000
HazardClass  6.1
PackingGroup  III
HS Code  29319090

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