A7451312
(2<i>S</i>,4<i>R</i>)-1-(<i>tert</i>-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid , >96.0%(T) , 203866-14-2
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB63.20 | In Stock |
|
| 1G | RMB125.60 | In Stock |
|
| 5g | RMB375.20 | In Stock |
|
| 10g | RMB631.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 115-119°C |
| Boiling point: | 346.0±42.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| refractive index | -69 ° (C=1, MeOH) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 3.53±0.40(Predicted) |
| color | White to Almost white |
| optical activity | [α]22/D -65.0±5°, c = 1 in chloroform |
| InChIKey | YGWZXQOYEBWUTH-RQJHMYQMSA-N |
Description and Uses
N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29339900 |
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