A7392912
SuberoylBis-hydroxamicAcid , 95% , 38937-66-5
Synonym(s):
N,N′-Dihydroxyoctanediamide;SBHA;SBHA - CAS 38937-66-5 - Calbiochem;Suberic Bishydroxamate, Suberoyl Bishydroxamic Acid, HDAC Inhibitor XII;Suberoyl bis-hydroxamic acid
| Pack Size | Price | Stock | Quantity |
| 200mg | RMB89.60 | In Stock |
|
| 1G | RMB287.20 | In Stock |
|
| 5G | RMB1006.40 | In Stock |
|
| 25g | RMB3523.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 153-155 °C(lit.) |
| Density | 1.219±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: soluble |
| pka | 9.18±0.20(Predicted) |
| form | lyophilized powder |
| color | White to Light Beige |
| Stability: | Hygroscopic |
Description and Uses
Suberohydroxamic acid (SBHA) is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50 = 0.25 μM) and HDAC3 (IC50 = 0.30 μM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. HDAC inhibitors, including SBHA, act synergistically to kill cancer cells when used in combination with cytostatic drugs, allowing lower doses of both inhibitors and drugs to be used.
Inhibits histone deacetylation.
Safety
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HS Code | 2928009090 |
