A7377212
Clopidogrel Bisulfate , ≥98% , 120202-66-6
Synonym(s):
(S)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogensulfate;(S)-(+)-Clopidogrel bisulfate;(S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfate;Clopidogrel Bisulphate;CLP
CAS NO.:120202-66-6
Empirical Formula: C16H16ClNO2S.H2O4S
Molecular Weight: 419.9
MDL number: MFCD00876395
EINECS: 1806241-263-5
Pack Size | Price | Stock | Quantity |
500MG | RMB272.00 | In Stock |
|
1g | RMB559.20 | In Stock |
|
5G | RMB2239.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 174-176°C |
storage temp. | 2-8°C |
solubility | DMSO: ~26 mg/mL |
form | solid |
color | white |
optical activity | [α]/D +54 to +70°, c = 0.5 in methanol |
BRN | 9967887 |
BCS Class | 2 |
InChIKey | FDEODCTUSIWGLK-RSAXXLAASA-N |
CAS DataBase Reference | 120202-66-6(CAS DataBase Reference) |
Description and Uses
(S)-(+)-Clopidogrel is the functional enantiomer of clopidogrel and a prodrug whose thiol metabolite antagonizes purine binding to the platelet purinergic receptor P2Y12 (Ki = 316 nM in human platelets). It is metabolized by the cytochrome P450 (CYP) isoform CYP2C19 in rat liver and inhibits ADP-induced platelet aggregation ex vivo. Formulations containing (S)-(+)-clopidogrel have been used in combination with aspirin to prevent vascular ischemic events in patients with acute coronary syndromes.
An irreversible inhibitor of P2Y12.
Safety
Symbol(GHS) | GHS07,GHS05,GHS09 |
Signal word | Danger |
Hazard statements | H335-H411-H362-H314 |
Precautionary statements | P201-P260-P263-P264-P270-P308+P313-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501 |
Safety Statements | 22-24/25 |
RIDADR | 1759 |
WGK Germany | 3 |
HazardClass | 8 |
PackingGroup | II |
HS Code | 29349990 |