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A5233012

Kanamycin sulfate , USPGrade, derived from Kanamycin chain mold , 25389-94-0

Synonym(s):
Kamycin;Kanamycin A;Kanamycin sulfate from Streptomyces kanamyceticus;Kanamycin sulfate salt;Kanamycin A

CAS NO.:25389-94-0

Empirical Formula: C18H38N4O15S

Molecular Weight: 582.58

MDL number: MFCD00070253

EINECS: 246-933-9

Pack Size Price Stock Quantity
1g RMB28.80 In Stock
5G RMB62.40 In Stock
25G RMB217.60 In Stock
100g RMB523.20 In Stock
500g RMB1990.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 250°C
alpha  +112~+123°(D/20℃)(c=1,H2O)(calculated on the dried basis)
Density  1.3619 (rough estimate)
refractive index  117.5 ° (C=1, H2O)
storage temp.  2-8°C
solubility  H2O: 10-50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.
form  powder
color  white to off-white
PH Range 6.5 - 8.5 (1% solution)
Water Solubility  Soluble in water at 10mg/ml
Merck  14,5281
InChIKey OOYGSFOGFJDDHP-KMCOLRRFSA-N

Description and Uses

Kanamycin was found by Umezawa et al. in the culture broth of Streptomyces kanamyceticus in 1957. It is produced with other components, kanamycins B (bekanamycin) and C, which are also separated during the purification. The compound shows much lower toxicity than the earlier aminoglycosides, streptomycin and neomycin, and strong activity against a wide range of gram-positive and gram-negative bacteria, including Mycobacterium. Kanamycin has been used clinically for treatment of such serious infections as dysentery, salmonellosis, and tuberculosis.

Kanamycin sulfate is an antibacterial agent similar to neomycin.

Safety

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360D
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  T
Risk Statements  61
Safety Statements  22-24/25-45-53
WGK Germany  3
RTECS  NZ3225030
HS Code  29419020
Toxicity LD50 in mice: 20.7 g/kg orally; 1450 mg/kg i.p. (Zel'tser)

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