Home Categories (S)-(-)-3-(Boc-amino)pyrrolidine
A7348712

(S)-(-)-3-(Boc-amino)pyrrolidine , 98% , 122536-76-9

Synonym(s):
tert-Butyl (S)-3-pyrrolidinylcarbamate

CAS NO.:122536-76-9

Empirical Formula: C9H18N2O2

Molecular Weight: 186.25

MDL number: MFCD00143194

EINECS: 628-488-6

Pack Size Price Stock Quantity
5G RMB150.40 In Stock
1g RMB215.20 In Stock
25G RMB575.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 50 °C
Boiling point: 112°C/0.25mm
Density  1.04±0.1 g/cm3(Predicted)
refractive index  -20 ° (C=1, EtOH)
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
pka 12.37±0.20(Predicted)
form  Powder
color  White to off-white
optical activity [α]/D -21.5±2.0°, c = 1 in ethanol
Water Solubility  Soluble in water.
Sensitive  Air Sensitive
BRN  5377813

Description and Uses

(S)-3-(Boc-amino)pyrrolidine can be used as a building block to prepare:

  • 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as potent inhibitors against EGFR tyrosine kinase.
  • Aminopyrrolidine scaffolds for asymmetric Morita?Baylis-Hillman reaction.
  • N-benzyl-3-sulfonamidopyrrolidines as potent bacterial cell division inhibitors.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,C
Risk Statements  36/37/38
Safety Statements  26
RIDADR  3259
WGK Germany  3
10-23
HazardClass  8
PackingGroup  III
HS Code  29339900

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