(S)-(-)-3-(Boc-amino)pyrrolidine , 98% , 122536-76-9

Synonym(s):
tert-Butyl (S)-3-pyrrolidinylcarbamate

CAS NO.：122536-76-9

Empirical Formula: C9H18N2O2

Molecular Weight: 186.25

MDL number: MFCD00143194

EINECS: 628-488-6

PRODUCT Properties

• Melting point: 50 °C
• Boiling point: 112°C/0.25mm
• Density: 1.04±0.1 g/cm3(Predicted)
• refractive index: -20 ° (C=1, EtOH)
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 12.37±0.20(Predicted)
• form: Powder
• color: White to off-white
• optical activity: [α]/D -21.5±2.0°, c = 1 in ethanol
• Water Solubility: Soluble in water.
• Sensitive: Air Sensitive
• BRN: 5377813
• CAS DataBase Reference: 122536-76-9(CAS DataBase Reference)

Description and Uses

(S)-3-(Boc-amino)pyrrolidine can be used as a building block to prepare:

• 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as potent inhibitors against EGFR tyrosine kinase.
• Aminopyrrolidine scaffolds for asymmetric Morita?Baylis-Hillman reaction.
• N-benzyl-3-sulfonamidopyrrolidines as potent bacterial cell division inhibitors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi,C
• Risk Statements: 36/37/38
• Safety Statements: 26
• RIDADR: 3259
• WGK Germany: 3
• F: 10-23
• HazardClass: 8
• PackingGroup: III
• HS Code: 29339900