Poly(vinylpyrrolidone)-Iodine complex , Reagent level , 25655-41-8

Synonym(s):
Povadyne antiseptic;PVP-I

CAS NO.：25655-41-8

Empirical Formula: C6H9I2NO

Molecular Weight: 364.95

MDL number: MFCD00084483

EINECS: 607-771-8

PRODUCT Properties

• Melting point: 300 °C
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: H2O: soluble100mg/mL
• form: Powder
• color: Yellow-brown
• Odor: ylsh. brn. amorphous powd., sl. char. odor
• Water Solubility: Soluble in water, ethyl alcohol, isopropyl alcohol, polyethylene glycol and glycerol. Insoluble in chloroform, carbon tetrachloride, hexane, acetone and petroleum ether.
• Merck: 13,7784
• InChI: InChI=1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2
• InChIKey: FAAHNQAYWKTLFD-UHFFFAOYSA-N
• SMILES: II.C(N1CCCC1=O)=C

Description and Uses

Povidone iodine is iodophor, used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. A 10% povidone iodine solution contains 1% available iodine, but free-iodine is at 0.1% concentration. Skin exposure causes irritant rather than allergic contact dermatitis. In such a situation, however, iodine seems to be the true hapten.

Polyvinylpyrrolidone-iodine complex is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine side chains. It is utilized to study microbial decontamination of human donor eyes as well as inactivation of infectious hematopoietic necrosis virus. It is also used as a carbon nanotube coating agent to enhance water solubility. It serves as a topical antiseptic in surgery, as an aerosol for skin and mucous membrane infections and is used to prevent infection in wounds.

Safety

• Symbol(GHS): GHS05,GHS09
• Signal word: Danger
• Hazard statements: H315-H318-H411
• Precautionary statements: P264-P273-P280-P302+P352-P305+P351+P338-P332+P313
• Safety Statements: 24/25-22
• WGK Germany: 2
• RTECS: TR1579600
• TSCA: Yes
• HS Code: 29339900