A7324912
Spermine , forcellculture,≥98.0%(GC) , 71-44-3
Synonym(s):
N,N′-Bis(3-aminopropyl)-1,4-diaminobutane;Gerontine;Musculamine;Neuridine
CAS NO.:71-44-3
Empirical Formula: C10H26N4
Molecular Weight: 202.34
MDL number: MFCD00012914
EINECS: 200-754-2
Pack Size | Price | Stock | Quantity |
1G | RMB396.80 | In Stock |
|
5G | RMB1594.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 28-30 (lit.) |
Boiling point: | 150 °C/5 mmHg (lit.) |
Density | 0.937 |
refractive index | 1.4850 (estimate) |
Flash point: | >230 °F |
storage temp. | 2-8°C |
solubility | H2O: 1 M at 20 °C, clear, colorless |
form | powder |
pka | 10.88±0.19(Predicted) |
color | Colorless to off-white |
Water Solubility | Soluble in chloroform, methanol, water and lower alcohols. Insoluble in ether, benzene and petroleum ether. |
Sensitive | Air Sensitive & Hygroscopic |
Merck | 14,8743 |
BRN | 1751791 |
Stability: | Hygroscopic |
InChIKey | PFNFFQXMRSDOHW-UHFFFAOYSA-N |
LogP | -0.543 (est) |
CAS DataBase Reference | 71-44-3(CAS DataBase Reference) |
NIST Chemistry Reference | Spermine(71-44-3) |
EPA Substance Registry System | 1,4-Butanediamine, N,N'-bis(3-aminopropyl)- (71-44-3) |
Description and Uses
Spermine is an endogenous polyamine synthesized from the reaction of spermidine with decarboxylated S-adenosylmethionine in the presence of the enzyme spermine synthase and is required for eukaryotic cell growth and protein synthesis. Intracellular spermine blocks inward rectifying K+ channels, whereas extracellular spermine acts as a mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Spermine has neuroprotective and anti-inflammatory effects and functions as a free radical scavenger to prevent DNA damage by reactive oxygen species.
immune modulator
Safety
Symbol(GHS) | GHS05 |
Signal word | Danger |
Hazard statements | H318-H314 |
Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P405-P501a-P280-P305+P351+P338-P310 |
Hazard Codes | Xi,C |
Risk Statements | 36/38-34 |
Safety Statements | 26-36-45-36/37/39-27 |
RIDADR | UN 3259 8/PG 2 |
WGK Germany | 3 |
RTECS | EJ7230000 |
F | 3-10 |
TSCA | Yes |
HazardClass | 8 |
PackingGroup | III |
HS Code | 29212900 |