Home Categories Biochemical Engineering Sodium 3-(3,4-dihydroxyphenyl)-DL-lactate
A7303512

Sodium 3-(3,4-dihydroxyphenyl)-DL-lactate , 98% , 67920-52-9

CAS NO.:67920-52-9

Empirical Formula: C9H11NaO5

Molecular Weight: 222.17

MDL number: MFCD07781415

EINECS: 804-287-0

Pack Size Price Stock Quantity
250MG RMB320.80 In Stock
1G RMB1030.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

storage temp.  Inert atmosphere,2-8°C
solubility  H2O : 100 mg/mL (454.24 mM; Need ultrasonic)DMSO : 100 mg/mL (454.24 mM; Need ultrasonic)
form  powder
color  White-beige

Description and Uses

Danshensu is a salvianolic acid and the major component of S. miltiorrhiza (Danshen) and has diverse biological activities. It reduces expression of the autophagy-associated proteins p62, LC3-II, and Beclin-1 and the apoptosis-related proteins Bax and caspase-3, prevents cardiomyocyte damage, and increases heart rate, coronary flow (CF), and left ventricular developed pressure (LVDP) in an isolated rat heart model of ischemia and reperfusion injury. Danshensu (60 mg/kg per day) reduces infarct size and improves left ventricular function in a rat model of myocardial infarction. It enhances radiation-induced tumor cell death in a Lewis lung carcinoma mouse xenograft model. Danshensu also decreases infarct volume, neuronal apoptosis, production of TNF-α, IL-1β, and IL-6, and superoxide dismutase (SOD) and glutathione peroxidase (GPx) activity in a rat model of cerebral ischemia and reperfusion injury.

Sodium Danshensu is exhibits protective effects on the excitotoxicity of monosodium glutamate in the late stage of pregnancy on developing mouse fetal brain.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25
HS Code  29329990

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