Home Categories Biochemical Engineering Rutaecarpine
A7117312

Rutaecarpine , Analysis of standard products, ≥98% , 84-26-4

Synonym(s):
8,13-Dihydro-indolo[2′,3′:3,4]pyrido[2,1-b]quinazolin-5(7H)-one;Rhetine;Rutecarpine

CAS NO.:84-26-4

Empirical Formula: C18H13N3O

Molecular Weight: 287.32

MDL number: MFCD00210551

EINECS: 635-907-6

Pack Size Price Stock Quantity
10MG RMB79.20 In Stock
20mg RMB136.00 In Stock
100mg RMB464.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 259.5-260°
Boiling point: 429.62°C (rough estimate)
Density  1.2030 (rough estimate)
refractive index  1.5855 (estimate)
storage temp.  Sealed in dry,2-8°C
solubility  DMSO: 18 mg/mL clear yellow solution, soluble
form  solid
pka 15.79±0.20(Predicted)
color  white
Merck  14,8298
InChIKey ACVGWSKVRYFWRP-UHFFFAOYSA-N

Description and Uses

This alkaloid occurs with Evodiamine (q.v.) in the Chinese drug 'Wou-chou-yu' which is the dried fruit of Evodia rutaecarpa Benth. It crystallizes from boiling EtOH as colourless, or pale yellow, needles and is optically inactive. The acetyl derivative has m.p. 184-6°C and the benzoyl compound, m.p. 194°C. The alkaloid gives a yellow colour with concentrated H2S04 and is decomposed by KOH in boiling amyl alcohol yielding anthranilic acid and 3-{3-aminoethylindole- 2-O!carboxylic acid, CllH120 2N2, silky crystals, m.p. 257°C.
Pharmacologically, the alkaloid causes increased arterial pressure on injection.

Rutaecarpine is an indole alkaloid contained in the fruit of Evodiae fruits. It been shown to ameliorate bodyweight gain through orexigenic neuropeptides NPY and AgRP. It also playes a role in the treatment of high blood pressure

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  T
Risk Statements  25-36/37/38
Safety Statements  45-36-26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  NM3454000
HS Code  29339900

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