(2R)-(−)-Glycidyl tosylate , 97% , 113826-06-5

Synonym(s):
(R)-(−)-Glycidyl p-toluenesulfonate;(R)-(−)-Glycidyl tosylate;(R)-(−)-Oxirane-2-methanol p-toluenesulfonate salt

CAS NO.：113826-06-5

Empirical Formula: C10H12O4S

Molecular Weight: 228.26

MDL number: MFCD00010834

EINECS: 601-283-9

PRODUCT Properties

• Melting point: 46-49 °C(lit.)
• alpha: -18 º (c=2.5,CHCl3)
• Boiling point: 340.07°C (rough estimate)
• Density: 1.3749 (rough estimate)
• refractive index: 1.5400 (estimate)
• Flash point: >230 °F
• storage temp.: 2-8°C
• solubility: dioxane: 50 mg/mL, clear
• form: powder
• color: yellow to orange
• Water Solubility: decomposes
• BRN: 3592142

Description and Uses

(2R)-(-)-Glycidyl tosylate may be used to prepare:

• 1-O-hexadecyl-sn-glycerol 3-O-p-toluenesulfonate by reacting with 1-hexadecanol in the presence of boron trifluoride etherate.
• 4-Oxiranylmethoxy-(1H)-indole by reacting with 4-hydroxyindole in the presence of sodium hydride.
• [¹⁸F]Epifluorohydin, an intermediate for preparing of [¹⁸F]fluoromisonidazole.

It can also be used as a starting material in the synthesis of 1,2-diacyl-sn-3-glycerophosphocholines.

Safety

• Symbol(GHS): GHS05,GHS07,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H317-H318-H341-H350-H411
• Precautionary statements: P201-P273-P280-P302+P352-P305+P351+P338+P310-P308+P313
• Hazard Codes: Xn,N,T
• Risk Statements: 45-41-43-51/53-68
• Safety Statements: 61-45-36/37/39-26-53
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• RTECS: RR0510000
• F: 3-10-21
• Hazard Note: Irritant
• HazardClass: 9
• HS Code: 29109000