PRODUCT Properties
Melting point: | 231-232° (U.S. patent); mp 238-239° (P'an) |
Boiling point: | 680.6±65.0 °C(Predicted) |
Density | 1.4176 (rough estimate) |
refractive index | 1.6100 (estimate) |
storage temp. | Refrigerator |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 9.57±0.20(Predicted) |
color | White to Off-White |
Water Solubility | 2.8mg/L(room temperature) |
EPA Substance Registry System | 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-[[(phenylmethyl)thio]methyl]-, 1,1-dioxide (91-33-8) |
Description and Uses
Benzthiazide is a diuretic, antihypertensive agent.
Safety
Symbol(GHS) | GHS08 |
Signal word | Danger |
Hazard statements | H317-H334 |
Precautionary statements | P261-P280-P342+P311 |
Hazard Codes | Xn |
Risk Statements | 42/43 |
Safety Statements | 26-36 |
WGK Germany | 2 |
RTECS | DK8400000 |
Hazardous Substances Data | 91-33-8(Hazardous Substances Data) |
Toxicity | LD50 in mice, rats (mg/kg): >5000, >10000 orally; 410, 422 i.v. (P'an) |