Ala-Gln , 10mMinWater , 39537-23-0
Synonym(s):
Ala-Gln;Alanyl-glutamine;Glutamine-S
CAS NO.：39537-23-0
Empirical Formula: C8H15N3O4
Molecular Weight: 217.22
MDL number: MFCD00133046
EINECS: 475-290-9
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 215 °C |
| Boiling point: | 615℃ |
| Density | 1.305±0.06 g/cm3(Predicted) |
| vapor pressure | 0-1000Pa at 20-313.7℃ |
| RTECS | MA2275262 |
| FEMA | 4712 | L-ALANYL-L-GLUTAMINE |
| refractive index | 10 ° (C=5, H2O) |
| Flash point: | >110°(230°F) |
| storage temp. | 2-8°C |
| solubility | Water (Sparingly) |
| form | solution |
| pka | 3.12±0.10(Predicted) |
| color | White |
| PH | pH(50g/l, 25℃) : 5.0～6.0 |
| Odor | mild savory |
| Water Solubility | Soluble in water. |
| JECFA Number | 2121 |
| Stability: | Hygroscopic |
| InChIKey | HJCMDXDYPOUFDY-AKGZTFGVSA-N |
| LogP | -4.6 at 22℃ and pH6.3 |
| Surface tension | 70mN/m at 1g/L and 20℃ |
Description and Uses
L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.
This supplement provides a stable form of L-glutamine while in solution.
Safety
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 23-24/25-36-26 |
| WGK Germany | 1 |
| HS Code | 29241990 |
