Bilirubin , 2mMinDMSO , 635-65-4

Synonym(s):
Bile pigment;Bilirubin - CAS 635-65-4 - Calbiochem;Hemetoidin

CAS NO.：635-65-4

Empirical Formula: C33H36N4O6

Molecular Weight: 584.66

MDL number: MFCD00005499

EINECS: 211-239-7

PRODUCT Properties

• Melting point: 192 °C
• Boiling point: 641.7°C (rough estimate)
• Density: 1.2163 (rough estimate)
• refractive index: 1.6000 (estimate)
• storage temp.: -20°C
• solubility: aqueous acid: soluble
• form: powder
• pka: 4.62±0.10(Predicted)
• color: orange
• Water Solubility: practically insoluble
• Sensitive: Light Sensitive
• Merck: 14,1218
• BRN: 74376
• Stability: Stable. Refrigerate.

Description and Uses

Bilirubin is a yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase. This reaction produces carbon monoxide and biliverdin, which is rapidly reduced to bilirubin by biliverdin reductase. Bilirubin has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions. Free and albumin-bound bilirubin can also scavenge nitric oxide (NO) and NO-related species. Unconjugated bilirubin is highly water-insoluble and must be conjugated with glucuronides to become water soluble and subsequently excreted by the liver and kidney.

Bilirubin has been used:

• in phantom preparation
• in in vitro experiments
• in the preparation of bilirubin solutions for infusion

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 62-36/37/38-20/21/22
• Safety Statements: 22-24/25-36-26
• WGK Germany: 2
• RTECS: DU3038000
• F: 8
• TSCA: Yes
• HS Code: 29339990