Acetyl-11-keto-β-BoswellicAcid,Boswelliaserrata , 10mMinDMSO , 67416-61-9
Synonym(s):
11-keto-β-Boswellic acid acetate;3α-Acetoxy-11-oxo-12-ursen-24-oic acid;3-O-Acetyl-11-keto-β-boswellic acid;AKBA
Pack Size | Price | Stock | Quantity |
1ml | RMB559.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 271℃ |
Boiling point: | 600.3±55.0 °C(Predicted) |
Density | 1.13±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | Chloroform (Sparingly), Methanol (Slightly) |
pka | 4.28±0.70(Predicted) |
form | Solid |
color | White to Off-White |
LogP | 7.418 (est) |
Description and Uses
3-acetyl-11-keto-β-Boswellic acid is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense). It selectively inhibits 5-lipoxygenase (IC50 = 1.5 μM) in an enzyme-directed, nonredox, and noncompetitive manner. 3-acetyl-11-keto-β-Boswellic acid and other members of the boswellic acid family have been studied for potential use in the control of inflammatory diseases, including arthritis and cancer.
3-Acetyl-11-keto-β-boswellic Acid (AKBA), be used in the place of the non-steroidal anti-inflammatory drug. AKBA, also inhibits human gastric carcinoma growth through modulation of the Wnt/β-catenin signaling pathway. It can be used as an anticancer agent.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Risk Statements | 36/37/38 |
Safety Statements | 26 |
WGK Germany | 3 |
HS Code | 2918300000 |