Home Categories Biochemical Engineering Ginsenoside Compound K
A4666712

Ginsenoside Compound K , 96%(HPLC) , 39262-14-1

CAS NO.:39262-14-1

Empirical Formula: C36H62O8

Molecular Weight: 622.88

MDL number: MFCD07772261

Pack Size Price Stock Quantity
5MG RMB319.20 In Stock
25MG RMB959.20 In Stock
50mg RMB1439.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 181~183℃
Boiling point: 723.1±60.0 °C(Predicted)
Density  1.19
solubility  DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
pka 12.94±0.70(Predicted)
form  powder
color  White
Stability: Hygroscopic
InChIKey FVIZARNDLVOMSU-SFEJUJENNA-N
LogP 5.500 (est)

Description and Uses

Ginsenoside compound K (C-K) is a metabolite of the protopanaxadiol-type saponins of Panax ginseng C.A. Meyer, has long been used to treat against the development of cancer, inflammation, allergies, and diabetes; C-K acts as a unique HUVEC migration inhibitor by regulating MMP expression, as well as the activity of SPHK1 and its related sphingolipid metabolites. C-K exhibits anti-inflammatory effects by reducing iNOS and COX-2, C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively. C-K promotes Aβ clearance by enhancing autophagy via the mTOR signaling pathway in primary astrocytes.

Ginsenoside C-K is reported to exhibit anti-wrinkle effects. Also, it potentiates tumor necrosis factor (TNF)-related apotosis-inducing ligand (TRAIL)-induced apotosis in HCT116 colon cancer.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501

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