Ginsenoside-Rb1 , Analysis of standards,> 98% , 41753-43-9

Synonym(s):
Arasaponin E1;Gynosaponin C;Gypenoside III;Notoginsenoside Rb1;Panaxoside Rb1

CAS NO.：41753-43-9

Empirical Formula: C54H92O23

Molecular Weight: 1109.29

MDL number: MFCD00133367

EINECS: 255-532-8

PRODUCT Properties

• Melting point: 197.5°C
• Boiling point: 766.35°C (rough estimate)
• Density: 1.0971 (rough estimate)
• refractive index: 1.6500 (estimate)
• storage temp.: 2-8°C
• solubility: methanol: soluble9.80 - 10.20 mg/mL, clear, colorless to faintly yellow
• pka: 12.85±0.70(Predicted)
• form: Solid
• color: Off-White to Pale Beige
• Stability: Hygroscopic
• InChIKey: GZYPWOGIYAIIPV-VOKNSFSUNA-N
• LogP: 2.900 (est)
• CAS DataBase Reference: 41753-43-9(CAS DataBase Reference)

Description and Uses

Ginsenoside Rb1, a glycosylated PPD type ginsenoside with two sugars linked to C-3 and two sugars linked to C-20, is the major active constituent of American ginseng. Studies have demonstrated the anti-aging effects of ginsenoside Rb1 at both animal and cell levels. 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD) is the major ingredient of ginsenoside Rb1, which has been shown to increase HAS2 expression by phosphorylating ERK and AKT signaling in human keratinocytes in a dose-dependent manner in vitro.

A major bioactive component of panax ginseng that promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway. It has been reported to display immunostimulatory and anticancer effects.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P501
• Hazard Codes: Xn,Xi,T,F
• Risk Statements: 20/21/22-39/23/24/25-23/24/25-11
• Safety Statements: 26-36-45-36/37-16-7
• WGK Germany: 3
• RTECS: LZ5856000
• HS Code: 29389090
• Toxicity: oms-rat-ipr 50 mg/kg CPBTAL 24,2400,76