Ginsenoside-Rb1 , Analysis of standards,> 98% , 41753-43-9
Synonym(s):
Arasaponin E1;Gynosaponin C;Gypenoside III;Notoginsenoside Rb1;Panaxoside Rb1
CAS NO.:41753-43-9
Empirical Formula: C54H92O23
Molecular Weight: 1109.29
MDL number: MFCD00133367
EINECS: 255-532-8
Pack Size | Price | Stock | Quantity |
20MG | RMB203.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 197.5°C |
Boiling point: | 766.35°C (rough estimate) |
Density | 1.0971 (rough estimate) |
refractive index | 1.6500 (estimate) |
storage temp. | 2-8°C |
solubility | methanol: soluble9.80 - 10.20 mg/mL, clear, colorless to faintly yellow |
form | Solid |
pka | 12.85±0.70(Predicted) |
color | Off-White to Pale Beige |
Stability: | Hygroscopic |
InChIKey | GZYPWOGIYAIIPV-VOKNSFSUNA-N |
LogP | 2.900 (est) |
Description and Uses
Ginsenoside Rb1, a glycosylated PPD type ginsenoside with two sugars linked to C-3 and two sugars linked to C-20, is the major active constituent of American ginseng. Studies have demonstrated the anti-aging effects of ginsenoside Rb1 at both animal and cell levels. 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD) is the major ingredient of ginsenoside Rb1, which has been shown to increase HAS2 expression by phosphorylating ERK and AKT signaling in human keratinocytes in a dose-dependent manner in vitro.
A major bioactive component of panax ginseng that promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway. It has been reported to display immunostimulatory and anticancer effects.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P501 |
Hazard Codes | Xn,Xi,T,F |
Risk Statements | 20/21/22-39/23/24/25-23/24/25-11 |
Safety Statements | 26-36-45-36/37-16-7 |
WGK Germany | 3 |
RTECS | LZ5856000 |
HS Code | 29389090 |
Toxicity | oms-rat-ipr 50 mg/kg CPBTAL 24,2400,76 |