GinsenosideRg2 , 10mMinDMSO , 52286-74-5

Synonym(s):
(3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside;Chikusetsusaponin I;Panaxoside Rg2;Prosapogenin C2

CAS NO.：52286-74-5

Empirical Formula: C42H72O13

Molecular Weight: 785.03

MDL number: MFCD00210511

PRODUCT Properties

• Melting point: 187～189℃
• Boiling point: 881.0±65.0 °C(Predicted)
• Density: 1.30±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Methanol (Slightly, Heated, Sonicated), Pyridine (Slightly, Sonicated)
• pka: 12.85±0.70(Predicted)
• form: Solid
• color: White to Off-White
• Stability: Hygroscopic
• InChIKey: AGBCLJAHARWNLA-DJZXLMSJSA-N
• LogP: 6.830 (est)

Description and Uses

Ginsenosides are pharmacologically active natural compounds from ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rg₂ is a protopanaxatriol that is more abundant in some Panax species (e.g., white and red P. ginseng) than others. This ginsenoside and its metabolites have diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-diabetic actions. It also protects against DNA damage and apoptosis induced by ultraviolet light. Notably, this ginsenoside is increased by the metabolism of other bioactive ginsenosides during the steaming or heating of plant materials, particularly in P. quinquefolium.

20(S)-Ginsenoside Rg2 is used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory activity. It exists as a bioactive metabolite of the ginsenoside component of Panax ginseng.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: LZ6430000
• HS Code: 29389090
• Toxicity: mouse,LD50,intraperitoneal,1340mg/kg (1340mg/kg),Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 343, 1975.