A7045058
CH5424802 , 10mMinDMSO , 1256580-46-7
CAS NO.：1256580-46-7
Empirical Formula: C30H34N4O2
Molecular Weight: 482.62
MDL number: MFCD19440988
EINECS: 821-541-6
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 274-276°C |
| Boiling point: | 722.5±60.0 °C(Predicted) |
| Density | 1.28 |
| storage temp. | -20° |
| solubility | Soluble in DMSO (up to 5 mg/ml with warming). |
| form | solid |
| pka | 13.70±0.40(Predicted) |
| color | White |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily. |
Description and Uses
Alectinib is another selective ALK inhibitor that is able to overcome resistance mutations from prior crizotinib exposure [38].
CH5424802 is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. CH5424802 have been clinically evaluated for the treatment of patients with ALK-driven tumors. Potent ALK inhibitor
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361-H341-H373 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501-P260-P314-P501 |
| HS Code | 2934999090 |
