Home Categories Biochemical Engineering Aurantio-obtusin
A7042258

Aurantio-obtusin , 10mMinDMSO , 67979-25-3

Synonym(s):
1,3,7-Trihydroxy-2,8-dimethoxy-6-methyl-9,10-anthracenedione

CAS NO.:67979-25-3

Empirical Formula: C17H14O7

Molecular Weight: 330.29

MDL number: MFCD13194886

Pack Size Price Stock Quantity
1ml RMB559.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 265-266 °C
Boiling point: 594.6±50.0 °C(Predicted)
Density  1.510±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Soluble in chloroform, DMSO and methan
form  powder
pka 6.32±0.20(Predicted)
color  Orange

Description and Uses

Aurantioobtusin is an anthraquinone originally isolated from Cassia seeds with diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro (IC50 = 13.6 μM). Aurantioobtusin (10 and 100 μM) activates the aryl hydrocarbon receptor (AhR) in a concentration-dependent manner. It inhibits rat platelet aggregation induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607), ADP, and collagen. Aurantioobtusin induces vasorelaxation in isolated precontracted rat mesenteric artery rings, an effect that is inhibited by the PI3K inhibitor LY290042 or inhibition of endothelial nitric oxide synthase (eNOS). It is larvicidal against A. gambiae mosquitoes (LD50 = 10 ppm).

A compound found in herbal remedies, believed to have an effect on blood platelet aggregation and lower blood lipid count

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Safety Statements  24/25
HS Code  29389090

RELATED PRODUCTS