A7028958
BGJ398(NVP-BGJ398) , 10mMinDMSO , 872511-34-7
CAS NO.：872511-34-7
Empirical Formula: C26H31Cl2N7O3
Molecular Weight: 560.48
MDL number: MFCD22123241
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >211°C (dec.) |
| Boiling point: | 747.9±60.0 °C(Predicted) |
| Density | 1.354 |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 5 mg/ml) |
| form | White solid. |
| pka | 11.02±0.70(Predicted) |
| color | White |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
Description and Uses
NVP-BGJ398 (872511-34-7) is a potent and selective pan-FGFR inhibitor (IC50?= 0.9nM, 1.4 nM, 1.0 nM, and 60 nM for FGFR1,2,3,4 respectively).1? It has also been used in a mouse model of Achondroplasia (most common form of dwarfism) to correct pathological hallmarks of this condition.
BGJ 398 is a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.
