A7012458
Amsacrinehydrochloride , 10mMinDMSO , 54301-15-4
Synonym(s):
m-AMSA;4-(9-Acridinylamino)-N-(methanesulfonyl)-m-anisidine hydrochloride
CAS NO.：54301-15-4
Empirical Formula: C21H20ClN3O3S
Molecular Weight: 429.92
MDL number: MFCD07799963
EINECS: 637-255-8
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 197-199 °C(lit.) |
| storage temp. | Refrigerator |
| solubility | DMSO: 10 mg/mL with heat and sonication |
| form | powder |
| color | red to brown |
Description and Uses
Amsacrine hydrochloride has been used:
- as a topoisomerase poison in bacteriophage T4 topoisomerase assay
- as a topoisomerase inhibitor in Drosophila cell line, Kc167
- as an antileukemia drug to test its effect on p53 transcriptional activity in tumor xenografts
- as a topoisomerase II poison in dose-response assays in C elegans
Safety
| Symbol(GHS) |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301-H317-H341-H351-H361d |
| Precautionary statements | P202-P261-P264-P280-P301+P310-P302+P352 |
| Hazard Codes | T |
| Risk Statements | 25-36/37/38 |
| Safety Statements | 26-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | PB1081000 |
| HS Code | 2933.99.8290 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
