A6983658
Cytosineβ-D-arabinofuranosidehydrochloride , 10mMinDMSO , 69-74-9
Synonym(s):
Cytarabine;Arabinosylcytosine;Ara-C;Cytarabine hydrochloride;Cytosine arabinoside
CAS NO.：69-74-9
Empirical Formula: C9H14ClN3O5
Molecular Weight: 279.68
MDL number: MFCD00012839
EINECS: 200-713-9
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 197-198 °C(lit.) |
| storage temp. | 2-8°C |
| solubility | insoluble in EtOH; ≥14.2 mg/mL in DMSO; ≥64.2 mg/mL in H2O |
| form | crystalline |
| color | White to off-white |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChI | InChI=1/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/s3 |
| InChIKey | KCURWTAZOZXKSJ-XKIMMOKZSA-N |
| SMILES | N1([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)C=CC(N)=NC1=O.[H]Cl |&1:1,3,6,8,r| |
Description and Uses
Cytosine beta-D-arabinofuranoside Hydrochloride is the salt form of Cytarabine, which is a selective inhibitor of DNA synthesis and is used as an antineoplastic and antiviral. Cytosine beta-D-arabinofuranoside Hydrochloride is used in chemotherapy for the treatment of white blood cells cancers such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma.
Antiviral.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H317-H319-H341-H361 |
| Precautionary statements | P201-P280-P302+P352-P305+P351+P338-P308+P313 |
| Hazard Codes | Xn |
| Risk Statements | 36-43-63 |
| Safety Statements | 26-36/37 |
| WGK Germany | 3 |
| RTECS | HA5500000 |
| HazardClass | IRRITANT |
| HS Code | 29389090 |
| Toxicity | LD50 oral in rat: > 3200mg/kg |
