7,12-Dimethylbenz[a]anthracene , 10mMinDMSO , 57-97-6

Synonym(s):
1,4-Dimethyl-2,3-benzophenanthrene;9,10-Dimethyl-1,2-benzanthracene;DMBA

CAS NO.：57-97-6

Empirical Formula: C20H16

Molecular Weight: 256.34

MDL number: MFCD00003600

EINECS: 200-359-5

PRODUCT Properties

• Melting point: 122-123 °C(lit.)
• Boiling point: 183-184 °C765 mm Hg(lit.)
• Density: 0.9 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.501(lit.)
• Flash point: 130 °F
• storage temp.: Sealed in dry,Room Temperature
• form: Crystalline Powder
• color: Yellow to greenish
• Merck: 14,3235
• BRN: 1912135
• CAS DataBase Reference: 57-97-6(CAS DataBase Reference)
• EPA Substance Registry System: 7,12-Dimethylbenz[a]anthracene (57-97-6)

Description and Uses

DBA is a greenish-yellow solid. Polynucleararomatic hydrocarbons (PAHs) are compounds containingmultiple benzene rings and are also called polycyclic aromatic hydrocarbons. Molecular weight= 256.36; Freezing/Melting point= 122℃. Insoluble in water

7,12-Dimethylbenz[a]anthracene was used:

• to study the effects of Cimicifuga racemosa (CR) extract on the growth of mammary tumor induced by 7,12-Dimethylbenz[a]anthracene
• in the study to compare the anti-carcinogenic properties of four red wine polyphenols as an initiator to cause skin cancer in CD-1 mouse model
• to induce epithelial carcinogenicity in order to study the apoptotic, proliferating and p12^doc-1 profiles of normal, hyperplastic, dysplastic and malignant oral epithelium in the cheek pouch of the Syrian hamster
• to cause mammary tumors to examine the causes and prevention of triacylglycerol accumulation in rat liver due to tamoxifen

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H350
• Precautionary statements: P201-P301+P312+P330-P308+P313
• Hazard Codes: T
• Risk Statements: 22-45
• Safety Statements: 45-53-36/37
• WGK Germany: 3
• RTECS: DP4500000
• F: 10-13-23
• HS Code: 29029090
• Hazardous Substances Data: 57-97-6(Hazardous Substances Data)