PRODUCT Properties
| Melting point: | 217-219 °C(lit.) |
| Boiling point: | 492.8±55.0 °C(Predicted) |
| Density | 1?+-.0.1 g/cm3(Predicted) |
| refractive index | 44 ° (C=1.4, H2O) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly) |
| form | Powder |
| pka | pK1:4.33 (25°C) |
| color | White to Off-white |
| Water Solubility | Soluble in water. |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 838-07-3(CAS DataBase Reference) |
Description and Uses
5-Methyl-2'-deoxycytidine is a nucleoside analogue that inhibits the synthesis of DNA. 5-Methyl-2'-deoxycytidine prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules.
5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25 |
| WGK Germany | 3 |
| RTECS | HA3860000 |
| HS Code | 29389090 |
