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A6948458

Dynasore , 10mMinDMSO , 304448-55-3

Synonym(s):
3-Hydroxynaphthalene-2-carboxylic acid-(3,4-dihydroxybenzylidene)-hydrazide, Sore to Dynamin;Dynamin Inhibitor I, Dynasore - CAS 304448-55-3 - Calbiochem

CAS NO.:304448-55-3

Empirical Formula: C18H14N2O4

Molecular Weight: 322.31

MDL number: MFCD00292551

EINECS: 200-256-5

Pack Size Price Stock Quantity
1ml RMB321.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >224°C (dec.)
Density  1.36±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 1 mg/ml).
form  Off-white solid.
pka 8.49±0.35(Predicted)
color  Beige
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Description and Uses

Dynasore (304448-55-3) is a noncompetitive inhibitor of dynamin GTPase activity and blocks dynamin-dependent endocytosis in cells, including neurons. It inhibits the GTPase activity of dynamin1, dynamin2, and Drp1 (mitochondrial dynamin). It is cell permeable, fast acting (seconds) and reversible.1,2 Dynasore is a extremely useful tool for studying endocytosis and other cellular events which are dependent on dynamin.3-5

Dynamin Inhibitor I, Dynasore is an inhibitor of Dynamin I and Dynamin II.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  N
Risk Statements  50
Safety Statements  22-24/25-61
RIDADR  UN 3077 9/PG 3
HS Code  2928.00.2500

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