A6847112
Phthalazone , ≥98.0% , 119-39-1
Synonym(s):
Benzo[d]pyridazin-1(2H)one
CAS NO.:119-39-1
Empirical Formula: C8H6N2O
Molecular Weight: 146.15
MDL number: MFCD00006892
EINECS: 204-319-8
Pack Size | Price | Stock | Quantity |
25G | RMB63.20 | In Stock |
|
100G | RMB191.20 | In Stock |
|
500G | RMB767.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 183-185 °C(lit.) |
Boiling point: | 337°C(lit.) |
Density | 1.2312 (rough estimate) |
refractive index | 1.4900 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
pka | 12.29±0.20(Predicted) |
form | Crystalline Powder |
color | Off-white to pale yellow |
BRN | 3654 |
InChIKey | IJAPPYDYQCXOEF-UHFFFAOYSA-N |
CAS DataBase Reference | 119-39-1(CAS DataBase Reference) |
EPA Substance Registry System | 1(2H)-Phthalazinone (119-39-1) |
Description and Uses
Phthalazone is a remarkable scaffold in drug discovery. Also, functions as an oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319 |
Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Hazard Codes | Xn |
Risk Statements | 22-68-36/37/38 |
Safety Statements | 22-24/25-36/37/39-26 |
WGK Germany | 3 |
RTECS | TH9185000 |
HazardClass | IRRITANT |
HS Code | 29339990 |
Hazardous Substances Data | 119-39-1(Hazardous Substances Data) |
Toxicity | mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00139, |