2,4-Piperidinedione , ≥97.0% , 50607-30-2

Synonym(s):
2,4-Diketopiperidine;2,4-Dioxopiperidine

CAS NO.：50607-30-2

Empirical Formula: C5H7NO2

Molecular Weight: 113.11

MDL number: MFCD08704814

EINECS: 803-771-9

PRODUCT Properties

• Melting point: 98.0 to 102.0 °C
• Boiling point: 362.1±35.0 °C(Predicted)
• Density: 1.184±0.06 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• form: powder to crystal
• pka: 12.00±0.70(Predicted)
• color: White to Orange to Green
• InChI: InChI=1S/C5H7NO2/c7-4-1-2-6-5(8)3-4/h1-3H2,(H,6,8)
• InChIKey: RDNZDMDLRIQQAX-UHFFFAOYSA-N
• SMILES: N1CCC(=O)CC1=O

Description and Uses

2,4-Piperidinedione is an important piperidine ring-containing intermediate, and its 2,4-piperidinedione, as a characteristic fragment, is widely used as an intermediate in the synthesis of ibrutinib and paliperidone drugs.

2,4-Piperidinedione is a reactant in the synthesis of 1,4-dihydropyridines as TGFβ/Smad inhibitors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H317-H319-H335
• Precautionary statements: P280-P301+P312+P330-P302+P352-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 22-36/37/38-43
• Safety Statements: 26-36/37
• RIDADR: UN 3335
• WGK Germany: 3
• HS Code: 2933790090