Pipemidic acid , 98% , 51940-44-4

Synonym(s):
8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid

CAS NO.：51940-44-4

Empirical Formula: C14H17N5O3

Molecular Weight: 303.32

MDL number: MFCD00057291

EINECS: 257-530-2

PRODUCT Properties

• Melting point: 251-255℃
• Boiling point: 717℃
• Density: 1.1931 (rough estimate)
• refractive index: 1.7000 (estimate)
• Flash point: >110°(230°F)
• storage temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• solubility: 1 M NaOH: soluble50mg/mL
• form: Powder
• pka: 4.14±0.20(Predicted)
• color: White to off-white
• Water Solubility: Soluble in 1N sodium hydroxide or in DMSO. Insoluble in water
• Sensitive: Light Sensitive

Description and Uses

Pipemidic acid is a quinolone antibacterial drug that is primarily used to treat gram-negative infections of the urinary tract. It is also an antibiotic and cell selection agent. Unlike nalidixic acid, pipemidic acid has a broader spectrum of antibacterial activity and is effective for treating urinary tract and ENT infections.

Safety

• Symbol(GHS): GHS08
• Signal word: Danger
• Hazard statements: H317-H334
• Precautionary statements: P280-P302+P352
• Hazard Codes: Xi
• Risk Statements: 42/43
• Safety Statements: 22-36/37-45
• WGK Germany: 2
• RTECS: UV1153800
• HS Code: 29335990
• Toxicity: LD50 in mice (mg/kg): 4000 orally; 1000 i.p., 50 i.v. (Ficicchia)